Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.943


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor



Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_48966394 1.950 TRABD
TraB domain containing
chr22_+_48966480 1.759 NM_025204
TRABD
TraB domain containing
chr7_+_94374862 1.192 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr1_-_173979292 1.078 NM_003285
TNR
tenascin R (restrictin, janusin)
chrX_-_138114100 1.049 FGF13
fibroblast growth factor 13
chr3_-_71196696 0.783 FOXP1
forkhead box P1
chr16_-_31135895 0.763 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr17_-_31831093 0.722 NM_001123392
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
TBC1 domain family, member 3F
chr22_+_16973556 0.695 TUBA8
tubulin, alpha 8
chrX_+_153423652 0.636 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr18_-_57711283 0.586 NM_173557
RNF152
ring finger protein 152
chr11_+_1170045 0.581 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr9_-_34554800 0.579 CNTFR
ciliary neurotrophic factor receptor
chr18_+_32021418 0.576 NM_017947
MOCOS
molybdenum cofactor sulfurase
chr1_+_61642287 0.562 NFIA
nuclear factor I/A
chr8_-_93184629 0.537 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr22_+_16973399 0.519 NM_001193414
NM_018943
TUBA8

tubulin, alpha 8

chrX_+_48221323 0.517 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr11_+_124115051 0.497 NRGN
neurogranin (protein kinase C substrate, RC3)
chr2_-_204108151 0.487 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr14_+_54238581 0.467 SAMD4A
sterile alpha motif domain containing 4A
chr17_-_33552166 0.433 NM_001123391
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr11_+_76516957 0.405 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr16_+_28797309 0.386 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr19_-_14121728 0.370 LPHN1
latrophilin 1
chr12_-_70953461 0.360 LOC283392
hypothetical LOC283392
chr15_+_89229275 0.358 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr1_-_226530350 0.351


chr19_-_56695458 0.344 NM_033329
SIGLEC12
sialic acid binding Ig-like lectin 12
chr14_-_63076155 0.333 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr18_+_44319365 0.328 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr9_+_139245029 0.322 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr4_-_123092358 0.320 NM_001130698
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr1_-_201420927 0.320 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr17_-_31528027 0.313 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr12_+_55896844 0.311 NM_007224
NXPH4
neurexophilin 4
chr1_+_46910086 0.308 NM_001145474
C1orf223
chromosome 1 open reading frame 223
chr2_+_238432925 0.302 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr14_+_94117483 0.297 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr19_-_63550712 0.293 A1BG
alpha-1-B glycoprotein
chr11_+_36572615 0.289 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr6_-_153494076 0.283 NM_012419
RGS17
regulator of G-protein signaling 17
chr3_-_54937001 0.280 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr2_-_217268492 0.278 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr5_-_92982927 0.272


chr3_-_59010777 0.263 C3orf67
chromosome 3 open reading frame 67
chr3_-_59010797 0.262 C3orf67
chromosome 3 open reading frame 67
chr2_+_220071780 0.260 NM_013335
NM_205847
GMPPA

GDP-mannose pyrophosphorylase A

chr17_-_33602374 0.259 NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr8_+_10420465 0.247 NM_001197020
NM_198464
PRSS55

protease, serine, 55

chr21_-_46399900 0.243 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr16_+_1974182 0.243 GFER
growth factor, augmenter of liver regeneration
chr1_+_77520874 0.237 NM_012093
AK5
adenylate kinase 5
chr20_-_39379533 0.236 ZHX3
zinc fingers and homeoboxes 3
chr3_-_59010740 0.236 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr5_-_178984192 0.235 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr5_-_72780107 0.231 NM_004472
FOXD1
forkhead box D1
chr4_-_84424921 0.227 COQ2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr17_-_39333490 0.225 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr1_+_156716290 0.224 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr11_+_131286513 0.219 NTM
neurotrimin
chr3_-_49117169 0.218 NM_005051
QARS
glutaminyl-tRNA synthetase
chr1_-_23623713 0.218 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr19_-_11355882 0.211 NM_000121
EPOR
erythropoietin receptor
chr9_+_115678365 0.211 NM_133374
ZNF618
zinc finger protein 618
chr1_-_1840564 0.209 NM_178545
TMEM52
transmembrane protein 52
chr11_-_65841077 0.208 NM_020404
CD248
CD248 molecule, endosialin
chr4_-_84424964 0.207 NM_015697
COQ2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr7_-_122126422 0.205 NM_139175
RNF133
ring finger protein 133
chr17_-_31616071 0.205 NM_001001418
NM_032258
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chrX_-_130250715 0.203 NM_001170963
IGSF1
immunoglobulin superfamily, member 1
chr19_+_12036513 0.201 NM_001136501
ZNF844
zinc finger protein 844
chr9_+_34448810 0.198 NM_012144
DNAI1
dynein, axonemal, intermediate chain 1
chr11_-_27679175 0.198 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr9_+_130838720 0.191 FAM73B
family with sequence similarity 73, member B
chr16_+_18986721 0.190 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr12_+_56299959 0.189 NM_133489
SLC26A10
solute carrier family 26, member 10
chr19_-_7244876 0.188 NM_000208
NM_001079817
INSR

insulin receptor

chr11_-_780103 0.187 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr19_-_12028126 0.185 NM_001080404
ZNF878
zinc finger protein 878
chr2_+_25118417 0.184 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr4_-_186693574 0.182 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr6_-_32253819 0.176 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr17_-_53964386 0.173 NM_080415
NM_080416
SEPT4

septin 4

chr6_-_68655708 0.172


chr11_+_64620276 0.166 C11orf2
chromosome 11 open reading frame 2
chr19_+_10652025 0.164


chr11_-_66945190 0.163 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr11_+_55884266 0.162 NM_001005205
OR8J1
olfactory receptor, family 8, subfamily J, member 1
chr11_+_64620183 0.162 NM_013265
C11orf2
chromosome 11 open reading frame 2
chr2_-_200028977 0.161 SATB2
SATB homeobox 2
chr1_-_33110668 0.160 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr11_+_64620287 0.157 C11orf2
chromosome 11 open reading frame 2
chr6_-_29081015 0.156 NM_001010877
ZNF311
zinc finger protein 311
chr13_+_49658016 0.154


chr1_+_99884018 0.154 NM_017734
PALMD
palmdelphin
chr11_-_73700257 0.154 NM_182904
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr6_-_32206029 0.154 NM_022110
FKBPL
FK506 binding protein like
chrX_+_16051344 0.152 NM_005314
GRPR
gastrin-releasing peptide receptor
chr11_+_63883192 0.147 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr19_+_47509274 0.145 NM_173633
TMEM145
transmembrane protein 145
chr9_+_138367329 0.145 NM_001145639
GPSM1
G-protein signaling modulator 1
chr5_-_180099663 0.143 NM_001001657
OR2Y1
olfactory receptor, family 2, subfamily Y, member 1
chr6_-_42124361 0.143 CCND3
cyclin D3
chr15_-_73017407 0.143 COX5A
cytochrome c oxidase subunit Va
chr11_-_63689780 0.142 MACROD1
MACRO domain containing 1
chr14_-_33489708 0.142 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr19_-_41090960 0.141 TYROBP
TYRO protein tyrosine kinase binding protein
chr15_-_73017439 0.140 NM_004255
COX5A
cytochrome c oxidase subunit Va
chr6_+_3697328 0.139


chr17_-_44043278 0.139 HOXB7
homeobox B7
chr8_+_22493928 0.136 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr11_-_57964221 0.136 NM_001004733
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr17_-_7023378 0.135 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr12_-_26166485 0.135 BHLHE41
basic helix-loop-helix family, member e41
chr19_+_44591589 0.131


chr10_+_102722275 0.131 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chrX_+_46825179 0.130 RGN
regucalcin (senescence marker protein-30)
chr19_+_40223249 0.128 NM_002151
NM_182983
HPN

hepsin

chr14_-_106352471 0.128


chr1_-_16217871 0.127 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr11_-_6397207 0.127 NM_145689
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_54244133 0.126 NM_033183
CGB
CGB5
CGB8
chorionic gonadotropin, beta polypeptide
chorionic gonadotropin, beta polypeptide 5
chorionic gonadotropin, beta polypeptide 8
chr20_+_337346 0.126 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr2_+_111206620 0.124 NM_001142807
ACOXL
acyl-CoA oxidase-like
chr12_+_52181643 0.123 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr12_-_55920741 0.122 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr17_+_2646481 0.120 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr7_-_94863558 0.120 NM_000940
PON3
paraoxonase 3
chr10_+_11087259 0.119 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr17_-_40401138 0.119 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr19_-_41091023 0.119 TYROBP
TYRO protein tyrosine kinase binding protein
chr11_+_101423378 0.119 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr17_-_53964360 0.118 SEPT4
septin 4
chr11_-_124311106 0.118 HEPACAM
hepatic and glial cell adhesion molecule
chrX_-_48661226 0.117 NM_006875
PIM2
pim-2 oncogene
chr5_+_131621230 0.117 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr1_+_93830169 0.116 LOC100129046
hypothetical LOC100129046
chr4_+_2764510 0.115 NM_001122681
SH3BP2
SH3-domain binding protein 2
chrX_-_39921525 0.115 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr1_-_27604656 0.113 WASF2
WAS protein family, member 2
chr1_+_77520315 0.113 NM_174858
AK5
adenylate kinase 5
chr16_+_55180767 0.112 NM_005954
MT3
metallothionein 3
chrX_+_153339814 0.112 NM_017514
PLXNA3
plexin A3
chr20_-_33658823 0.111 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr1_+_93830106 0.111 LOC100129046
hypothetical LOC100129046
chrX_-_71443308 0.110 NM_004143
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_-_41091045 0.109 NM_001173514
NM_001173515
NM_003332
NM_198125
TYROBP



TYRO protein tyrosine kinase binding protein



chr3_+_156280129 0.107 NM_000902
MME
membrane metallo-endopeptidase
chr10_-_43212166 0.107 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_166960690 0.106 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_66519949 0.106 MEIS1
Meis homeobox 1
chr11_+_10480891 0.105 AMPD3
adenosine monophosphate deaminase 3
chr7_-_124192265 0.104 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr12_-_6668085 0.104 NM_001039916
ZNF384
zinc finger protein 384
chr8_+_94998258 0.103 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr9_-_135593265 0.102 NM_001134707
SARDH
sarcosine dehydrogenase
chr7_+_97679501 0.100 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr1_-_20122638 0.100 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr16_-_10581944 0.099 NM_001424
EMP2
epithelial membrane protein 2
chr14_+_94117511 0.097 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr10_-_33663984 0.097 NRP1
neuropilin 1
chr21_-_45165249 0.096 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_26220895 0.095 EXTL1
exostoses (multiple)-like 1
chr16_+_11978002 0.093 NM_032167
RUNDC2A
RUN domain containing 2A
chr2_-_27457088 0.093 NM_144631
ZNF513
zinc finger protein 513
chr15_-_73036179 0.091 RPP25
ribonuclease P/MRP 25kDa subunit
chr17_+_75507750 0.091


chr3_+_191588354 0.090 NM_006580
CLDN16
claudin 16
chr20_+_41628150 0.090 NM_016276
SGK2
serum/glucocorticoid regulated kinase 2
chr6_-_166960496 0.090 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr21_+_30937053 0.090 NM_001128077
KRTAP20-3
keratin associated protein 20-3
chr6_-_132314004 0.089 NM_001901
CTGF
connective tissue growth factor
chr14_-_34661387 0.089 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_139027435 0.089 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_-_139995417 0.088 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr12_+_109536214 0.088 NM_001082537
NM_001082538
NM_001173976
NM_024549
NM_001173975
TCTN1




tectonic family member 1




chr7_-_120285364 0.086 NM_012338
TSPAN12
tetraspanin 12
chr17_+_45008473 0.085 NXPH3
neurexophilin 3
chr19_-_47451119 0.085 NM_006494
ERF
Ets2 repressor factor
chr12_+_131577229 0.085 NM_001142641
FBRSL1
fibrosin-like 1
chr4_+_6726555 0.084 LOC93622
hypothetical LOC93622
chr17_+_72958920 0.084 SEPT9
septin 9
chr1_-_152741148 0.083 NM_001010846
SHE
Src homology 2 domain containing E
chr1_-_33139425 0.082 NM_033504
TMEM54
transmembrane protein 54
chr4_+_6726699 0.081 LOC93622
hypothetical LOC93622
chr21_-_45165204 0.080 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_227473458 0.080 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr19_-_56164628 0.080 NM_002774
KLK6
kallikrein-related peptidase 6
chr6_-_91063181 0.080 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr17_-_74990157 0.079 NM_001082575
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr19_-_18868395 0.079 LASS1
LAG1 homolog, ceramide synthase 1
chr14_+_49429474 0.079 NM_001663
ARF6
ADP-ribosylation factor 6
chr17_-_77640237 0.079


chr1_+_226420437 0.078 C1orf69
chromosome 1 open reading frame 69
chr14_-_100420936 0.078 NM_001134888
RTL1
retrotransposon-like 1
chr2_-_80384454 0.077 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_+_152741318 0.077 NM_001098475
NM_182499
TDRD10

tudor domain containing 10

chr22_-_42619139 0.076 NM_001177675
NM_138814
PNPLA5

patatin-like phospholipase domain containing 5

chr16_+_15950707 0.076 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1





Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
9.88 1.30e-02 GO:0007399 nervous system development

Nothing significant found in compartment category.

Nothing significant found in function category.